Addressing the industry pain points of low exosome purification efficiency and high background interference, Yocon has introduced a large-scale stem cell exosome production solution based on "GMP-grade serum-free medium for mesenchymal stem cells + mesenchymal stem cell exosome enhancer + porous hollow microcarriers + exosome culture workstation". The newly upgraded 2.0 version of the GMP-grade serum-free medium for mesenchymal stem cells features a fully defined chemical composition, significantly improved cell adherence and adaptability, supports lower seeding densities and higher amplification multiples, and is compatible with 2D and 3D large-scale culture modes such as cell factories, microcarriers, and bioreactors, facilitating the harvest of higher yields of exosomes. The exosome enhancer can increase exosome secretion by 2 to 5 times under unchanged original culture conditions, rapidly boosting production volumes! The porous hollow microcarriers are microcarrier products specifically designed for stem cells, used for large-scale culture of adherent cells in bioreactors. They provide a vast adhesion area for stem cells, efficiently increasing the number of cultured cells and the harvest of secreted products. The exosome culture workstation, developed specifically for small-to-medium-scale users, is equipped with a disposable tubing system pre-loaded with sheet-like microcarriers. Through intermittent shaking and a closed tubing design, it achieves fully automated production in 15 days, with a single batch yielding 250 trillion high-purity exosomes.
